Gene
gfer
- ID
- ZDB-GENE-060810-186
- Name
- growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)
- Symbol
- gfer Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Exhibits flavin-linked sulfhydryl oxidase activity and identical protein binding activity. Involved in heart development and liver development. Localizes to mitochondrion. Human ortholog(s) of this gene implicated in kidney failure and renal fibrosis. Is expressed in several structures, including fin; gill; head; liver and biliary system; and pleuroperitoneal region. Orthologous to human GFER (growth factor, augmenter of liver regeneration).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7163713 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Li et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Myopathy, mitochondrial progressive, with congenital cataract and developmental delay | 613076 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ERV/ALR sulfhydryl oxidase domain | ERV/ALR sulfhydryl oxidase domain superfamily | Sulfhydryl oxidase ALR/ERV |
|---|---|---|---|---|
|
UniProtKB:A4QNU9
|
191 |
Interactions and Pathways
No data available
Plasmids
No data available